The Clarke Courier of 3 November 1909 reported private advice from railway officials that a depot promised for Berryville — "sadly needed for so long" — would not be long in starting, and would be one of the best on the system1. Two months later, on 5 January 1910, the paper carried the headline 'New Depot Assured' over a report that the railway board had passed the Berryville depot, that it was next on the list to be erected, and that work would start when the spring weather opened. The article placed the station on McCormick land south of the turnpike and described steam heat, electric light, and accommodation for passengers, baggage, express and freight2.
Work started on Monday 2 March 1910, with a large force of men preparing the ground for the foundations1. In May the Courier named O. L. Burnett of the J. P. Pettijohn Company of Lynchburg as contractor, reported the railway's deadline of 1 August, and described excavation for foundations and cellar and a trench for a water line run from the Main Street main2. By 27 July the depot was described as rapidly nearing completion, with outside painting finished and painters at work inside. On 10 August the Courier reported the finishing touches under way and Station Agent Macomb expecting to move in 'next Sunday if everything goes well'3. What Sunday it opened, and whether Macomb kept his prediction, the record on this site does not settle.
The 1987 Berryville Historic District nomination inventoried the building as a brick station with a hipped roof, bracketed eaves, and iron grillwork over the main windows — Tudor Revival, 1910, and vacant by 19871. A 2024 Clarke Monthly report explains the geography the earlier record blurs: the first railway station, north of Main Street on First Street, handled both freight and passengers until 1910, when the Norfolk and Western built the passenger station south of Main Street on Station Avenue opposite the gristmill; the older First Street station continued as a freight station2.
Norfolk Southern Corporation demolished the passenger station on 2 July 1990, after two years in which the Berryville-Clarke County Chamber of Commerce had negotiated to take the building as a visitors' centre. The railroad had been willing to donate the building but not its land, and the negotiation failed on that condition1. Souvenir hunters took bricks and iron window guards after the demolition. One guard ended up at Hip and Humble in the mill opposite the site, Berryville Main Street acquired it in 2023, and a town crew installed it at the Main Street entrance to Hogan's Alley in mid-March 2024. Virginia Main Street separately describes the guard as repaired at a local welder's school and installed at the alley's northern entrance2.
Nine claims across the depot's whole life, from the 1909 rumor of its coming to the 2024 reappearance of one iron window guard. The Norfolk & Western built it, the town spent eighty years using it, the railway spent two years failing to give it away, and it fell in one morning in July 1990. What sits on Station Avenue today, and what the site looked like in the years between the demolition and 2024, are questions this collection has not yet opened.